Sonaglioni A, Baravelli M, Vincenti A et al (2018) A New modified anthropometric haller index obtained without radiological exposure. Sonaglioni A, Nicolosi GL, Granato A, Lombardo M, Anzà C, Ambrosio G (2020) Reduced myocardial strain parameters in subjects with pectus excavatum: impaired myocardial function or methodological limitations due to chest deformity? Semin Thorac Cardiovasc Surg S1043–0679(20):30127–30131 Malev E, Zemtsovsky E, Pshepiy A, Timofeev E, Reeva S, Prokudina M (2012) Evaluation of left ventricular systolic function in young adults with mitral valve prolapse. Eur J Heart Fail 13:292–302įukuda S, Song JK, Mahara K et al (2016) Basal left ventricular dilatation and reduced contraction in patients with mitral valve prolapse can be secondary to annular dilatation: preoperative and postoperative speckle-tracking echocardiographic study on left ventricle and mitral valve annulus interaction. J Am Soc Echocardiogr 23:1025–1034Ĭarluccio E, Biagioli P, Alunni G et al (2011) Advantages of deformation indices over systolic velocities in assessment of longitudinal systolic function in patients with heart failure and normal ejection fraction. Int J Cardiol 132:11–24Ĭarerj S, La Carrubba S, Antonini-Canterin F et al (2010) The incremental prognostic value of echocardiography in asymptomatic stage a heart failure. J Am Soc Echocardiogr 18:1440–1463ĭandel M, Hetzer R (2009) Echocardiographic strain and strain rate imaging-clinical applications. Lang RM, Bierig M, Devereux RB et al (2005) Recommendations for chamber quantification: a report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. Hayek E, Gring CN, Griffin BP (2005) Mitral valve prolapse. Zuppiroli A, Rinaldi M, Kramer-Fox R, Favilli S, Roman MJ, Devereux RB (1995) Natural history of mitral valve prolapse. Circulation 129:2158-2170ĭevereux RB, Kramer-Fox R, Shear MK, Kligfield P, Pini R, Savage DD (1987) Diagnosis and classification of severity of mitral valve prolapse: methodologic, biologic, and prognostic considerations. J Am Coll Cardiol 40:1298-1304ĭelling FN, Vasan RS (2014) Epidemiology and pathophysiology of mitral valve prolapse: new insights into disease progression, genetics, and molecular basis. N Engl J Med 341:1-7įreed LA, Benjamin EJ, Levy D et al (2002) Mitral valve prolapse in the general population: the benign nature of echocardiographic features in the Framingham Heart Study. Tricuspid annular plane systolic excursion TTE:įreed LA, Levy D, Levine RA et al (1999) Prevalence and clinical outcome of mitral-valve prolapse. Right ventricular end-diastolic diameter RWT: Nonspecific ST-segment and T-wave abnormalities PE: In MVP subjects, impairment of myocardial strain parameters is not due to intrinsic reduction of cardiac contractility function, but it appears to be related to the degree of chest deformity. A significant impairment in myocardial strain parameters and LV peak twist was documented in MVP subjects with MHI > 2.5, but not in those with MHI ≤ 2.5. MHI was significantly greater in MVP group than controls (2.6 ± 0.35 vs 2.1 ± 0.23, p 2.5, n = 30), and those with MHI ≤ 2.5 (n = 30) were then separately analyzed. Participants underwent modified Haller index (MHI) assessment (ratio of chest transverse diameter over the distance between sternum and spine), and transthoracic echocardiography implemented with 2D-speckle tracking analysis. Between April 2019 and May 2020, 60 healthy subjects (50.1 ± 8.6 year/old, 46.6% females) with MVP and mild-to-moderate mitral regurgitation, and 60 controls matched by age, sex, and cardiovascular risk factors were consecutively studied. However, the relationship between myocardial strain parameters and chest conformation has not been previously investigated in subjects with mitral valve prolapse (MVP). Chest shape might affect myocardial strain parameters.